Much has been written about resolution scaling in pixel art games. It usually comes down to this simplistic rule: always resize 2D games by integer values (2x, 3x, 4x, 5x, etc) so pixel art will always look correct.
I wrote that myself; to make a good looking low-res pixel art game on modern monitors, you should stick with a 384×216 resolution and scale it up 5 times to get a perfect 1920×1080 (1080p) game.
That’s still true-ish. But the problem I was trying to address wasn’t pixel distortion. It was pixel decimation. Let’s see how to solve it using any resolution you want to use.